2-Chloro-5-aMinobenzoic acid Methyl ester
Methyl 5-amino-2-chlorobenzoate
CAS: 42122-75-8
Molecular Formula: C8H8ClNO2
2-Chloro-5-aMinobenzoic acid Methyl ester - Names and Identifiers
2-Chloro-5-aMinobenzoic acid Methyl ester - Physico-chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molar Mass | 185.61 |
| Density | 1.311 |
| Melting Point | 68-70℃ |
| Boling Point | 320℃ |
| Flash Point | 147℃ |
| Vapor Presure | 0.000333mmHg at 25°C |
| pKa | 2.81±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.58 |
2-Chloro-5-aMinobenzoic acid Methyl ester - Introduction
Methyl 5-amino-2-chlorophyll (Methyl 5-amino-2-chlorophyll) is an organic compound. Its chemical formula is C8H8ClNO2 and its relative molecular mass is 187.61g/mol. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White to light yellow crystal
-Melting point: 106-110°C
-Thermal stability: will decompose at high temperatures
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use:
- Methyl 5-amino-2-chorobenzoate is mainly used in organic synthesis as chemical reagents, intermediates and raw materials for synthetic materials.
-It can be used to prepare other compounds containing chlorine and amino substituents.
Preparation Method:
Methyl 5-amino-2-chlorobenzoate can be prepared by the following steps:
1. mix methyl formate with nitric acid and add hydrochloric acid and glacial acetic acid solution;
2. Add 2-chloro-5-aminobenzene borate and continue to stir the reaction mixture;
3. add hydrochloric acid solution for neutralization, and filter the white solid;
4. Dry the solid crystals obtained by filtration to obtain Methyl 5-amino-2-chlorobenzoate.
Safety Information:
- Methyl 5-amino-2-chorobenzoate may be irritating to the eyes, skin and respiratory system and should be avoided.
-Follow proper laboratory procedures and wear appropriate personal protective equipment, such as gloves and protective glasses.
-Avoid contact with oxidants and strong alkalis during storage, and keep the container sealed and placed in a dry and cool place.
Nature:
-Appearance: White to light yellow crystal
-Melting point: 106-110°C
-Thermal stability: will decompose at high temperatures
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use:
- Methyl 5-amino-2-chorobenzoate is mainly used in organic synthesis as chemical reagents, intermediates and raw materials for synthetic materials.
-It can be used to prepare other compounds containing chlorine and amino substituents.
Preparation Method:
Methyl 5-amino-2-chlorobenzoate can be prepared by the following steps:
1. mix methyl formate with nitric acid and add hydrochloric acid and glacial acetic acid solution;
2. Add 2-chloro-5-aminobenzene borate and continue to stir the reaction mixture;
3. add hydrochloric acid solution for neutralization, and filter the white solid;
4. Dry the solid crystals obtained by filtration to obtain Methyl 5-amino-2-chlorobenzoate.
Safety Information:
- Methyl 5-amino-2-chorobenzoate may be irritating to the eyes, skin and respiratory system and should be avoided.
-Follow proper laboratory procedures and wear appropriate personal protective equipment, such as gloves and protective glasses.
-Avoid contact with oxidants and strong alkalis during storage, and keep the container sealed and placed in a dry and cool place.
Last Update：2024-04-10 22:29:15
